Experimental Studies with Animals
regard to in vivo
animal studies, one of the most significant RF effects to be reported
is disruption of the blood-brain barrier (BBB). This was reported in
small laboratory animals in less than 30% of reviewed studies.
However, most well controlled studies have not reported these effects
and it seems that the positive results could be explained more simply
by uncontrolled effects of heating. Further, the translation of such
results to human beings, with entirely different cranial geometries
and blood flow, is very doubtful.
induction and promotion of tumors or blood neoplasms by RF exposure
in animals as well as the appearance of cellular molecular
predecessors of tumorigenesis, etc. has also been investigated.
Despite using RF exposures, measured as specific absorption rates
(SARs), far above those that people are normally exposed to, and in
some cases exposures for the duration of the animal’s lifetime,
about 93% of in vivo
studies published since 1990 have shown no significant short or
long-term effects. Further, the average survival of irradiated groups
of animals was not affected in some 96% of studies.
convincing evidence has been presented for RF acute or chronic
effects of RF on other physiological and biochemical parameters in
animals. Thus, the general conclusion, after more than 20 years of in
vivo studies, is that no consistent or
important effects of RF could be demonstrated in intact animals below
international safety standards. There seems to be no important
pathophysiological effect of RF fields, apart from thermal effects
caused by exposure to fields many times larger than those encountered
in our living and working environments.
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